Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713206 | 1.00 | PPARG (0.48) | PPARGEPHX2PPARAPPARDTDP1 | |
| SCHEMBL13941150 | 0.88 | DDR1 (0.38) | PPARGEPHX2PPARATDP1DDR1 | |
| SCHEMBL12713207 | 0.84 | EPHX2 (0.43) | PPARGEPHX2PPARAPPARDTDP1 | |
| SCHEMBL13941324 | 0.83 | PPARA (0.44) | PPARGEPHX2PPARAPPARDTDP1 | |
| SCHEMBL12713224 | 0.82 | PPARG (0.47) | PPARGEPHX2PPARAPPARDTDP1 | |
| SCHEMBL12713189 | 0.81 | PPARA (0.43) | PPARGPPARACYP1A2CYP2C9KDM4E | |
| SCHEMBL10745481 | 0.80 | PPARG (0.49) | PPARGEPHX2PPARAPPARDTDP1 | |
| SCHEMBL31276470 | 0.78 | CYP2C9 (0.49) | PPARGPPARATDP1LMNACYP1A2 | |
| SCHEMBL1511311 | 0.78 | PPARG (0.49) | PPARGEPHX2PPARAPPARDCYP1A2 | |
| SCHEMBL12713191 | 0.75 | PPARA (0.37) | PPARGPPARADDR1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |