Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468973 | 0.81 | TSHR (0.50) | PPARGPPARATSHRHTR2AHTR2C | |
| SCHEMBL6468980 | 0.81 | TSHR (0.50) | PPARGPPARATSHRHTR2AHTR2C | |
| SCHEMBL14435214 | 0.80 | PPARG (0.48) | PPARGEPHX2PPARAPPARDTDP1 | |
| SCHEMBL12713206 | 0.80 | PPARG (0.48) | PPARGEPHX2PPARAPPARDTDP1 | |
| SCHEMBL2899349 | 0.79 | CYP2C9 (0.48) | TSHRHTR2AHTR2CHTR2BPOLB | |
| SCHEMBL12713285 | 0.79 | CYP2C9 (0.48) | TSHRHTR2AHTR2CHTR2BPOLB | |
| SCHEMBL2797496 | 0.79 | CYP2C9 (0.48) | TSHRHTR2AHTR2CHTR2BPOLB | |
| SCHEMBL12713283 | 0.79 | CYP2C9 (0.48) | TSHRHTR2AHTR2CHTR2BPOLB | |
| SCHEMBL9419792 | 0.77 | PPARG (0.64) | PPARGEPHX2PPARAALDH1A1HTT | |
| SCHEMBL15446333 | 0.76 | PPARA (0.52) | PPARGPPARATSHRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4654363-A | Synthetic analogs of mevinolin | MERCK & CO., INC. (US) | 1987-03-31 | — | — | US | disclosed |