Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435250 | 0.92 | F10 (0.51) | F10SLC2A1KLKB1POLBHTR2C | |
| SCHEMBL14434231 | 0.88 | F10 (0.46) | F10SLC2A1KLKB1POLBMELK | |
| SCHEMBL14435246 | 0.83 | MELK (0.47) | F10SLC2A1KLKB1POLBMELK | |
| SCHEMBL14434686 | 0.83 | SLC2A1 (0.51) | F10SLC2A1KLKB1POLBMELK | |
| SCHEMBL12101325 | 0.83 | F10 (0.51) | F10SLC2A1KLKB1POLBMELK | |
| SCHEMBL12371440 | 0.82 | F10 (0.54) | F10KLKB1POLBHTR2C | |
| SCHEMBL12371443 | 0.82 | F10 (0.51) | F10KLKB1POLBHTR2C | |
| SCHEMBL14434688 | 0.81 | F10 (0.43) | F10SLC2A1KLKB1POLBMELK | |
| SCHEMBL14434689 | 0.80 | SLC2A1 (0.48) | F10SLC2A1KLKB1POLBMELK | |
| SCHEMBL14434228 | 0.79 | F10 (0.44) | F10SLC2A1KLKB1POLBMELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093595-A1 | SUBSTITUTED PROLINAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |