Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772286 | 0.90 | PRKCA (0.54) | PRKCAMMP12NR1I2SRD5A2SCN9A | |
| SCHEMBL4826803 | 0.89 | PRKCA (0.51) | PRKCAMMP12NR1I2SRD5A2SCN9A | |
| SCHEMBL13940284 | 0.86 | PRKCA (0.49) | PRKCAMMP12NR1I2SRD5A2SCN9A | |
| SCHEMBL772130 | 0.83 | PRKCA (0.53) | PRKCAMMP12NR1I2SRD5A2SCN9A | |
| SCHEMBL773872 | 0.83 | PRKCA (0.53) | PRKCAMMP12NR1I2SRD5A2SCN9A | |
| SCHEMBL896011 | 0.82 | PRKCA (0.51) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL30065382 | 0.82 | PRKCA (0.51) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3085838 | 0.81 | PRKCA (0.51) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL894955 | 0.81 | PRKCA (0.47) | PRKCAMMP12NR1I2SRD5A2SCN9A | |
| SCHEMBL4830061 | 0.81 | PRKCA (0.55) | PRKCAMMP12NR1I2SRD5A2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007033175-A1 | INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |