Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435351 | 0.91 | SCN9A (0.67) | SCN9ANR1I2SCN5AKCNH2 | |
| SCHEMBL14253484 | 0.89 | SCN9A (0.50) | SCN9ANR1I2CCKBRKCNH2 | |
| SCHEMBL4831416 | 0.84 | NR1I2 (0.60) | SCN9ANR1I2PRKCAMMP12SCN5A | |
| SCHEMBL14253480 | 0.83 | NR1I2 (0.59) | SCN9ANR1I2PRKCAMMP12SCN5A | |
| SCHEMBL14435391 | 0.83 | NR1I2 (0.58) | SCN9ANR1I2PRKCAMMP12SCN5A | |
| SCHEMBL14253483 | 0.82 | SCN9A (0.55) | SCN9ANR1I2PRKCAMMP12SCN5A | |
| SCHEMBL14253481 | 0.81 | SCN9A (0.62) | SCN9ANR1I2SCN5ACYP3A4CYP2C9 | |
| SCHEMBL12427557 | 0.81 | PRKCA (0.51) | SCN9ANR1I2PRKCAMMP12CCKBR | |
| SCHEMBL14253535 | 0.81 | SCN9A (0.61) | SCN9ANR1I2SCN5AKCNH2 | |
| SCHEMBL14253463 | 0.80 | NR1I2 (0.56) | SCN9ANR1I2PRKCAMMP12SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |