⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amifampridine SCHEMBL21273 | 0.80 | — | — | |
| Amifampridine SCHEMBL29354458 | 0.80 | — | — | |
| Amifampridine SCHEMBL30609183 | 0.78 | — | — | |
| Amifampridine SCHEMBL8907371 | 0.78 | GAA (0.56) | — | |
| Amifampridine SCHEMBL28271256 | 0.78 | — | — | |
| Amifampridine SCHEMBL19410631 | 0.78 | GAA (0.56) | — | |
| Amifampridine SCHEMBL11016903 | 0.78 | — | — | |
| Amifampridine SCHEMBL8907368 | 0.78 | GAA (0.56) | — | |
| Amifampridine SCHEMBL28271266 | 0.76 | GAA (0.54) | — | |
| Amifampridine SCHEMBL27516080 | 0.74 | GAA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |