Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Amifampridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amifampridine SCHEMBL21273 | 1.00 | — | — | |
| Amifampridine SCHEMBL8907371 | 0.97 | GAA (0.56) | — | |
| Amifampridine SCHEMBL30609183 | 0.97 | — | — | |
| Amifampridine SCHEMBL28271256 | 0.97 | — | — | |
| Amifampridine SCHEMBL11016903 | 0.97 | — | — | |
| Amifampridine SCHEMBL8907368 | 0.97 | GAA (0.56) | — | |
| Amifampridine SCHEMBL19410631 | 0.97 | GAA (0.56) | — | |
| Amifampridine SCHEMBL28271266 | 0.94 | GAA (0.54) | — | |
| Amifampridine SCHEMBL27516080 | 0.92 | GAA (0.52) | — | |
| Amifampridine SCHEMBL5308533 | 0.89 | ALDH1A1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 940 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731135-A1 | ADJUSTMENT DEVICE FOR ADJUSTING A JOINT PROSTHESIS | Guerin, Geoffroy (FR) | 2026-04-29 | — | — | EP | claimed |
| US-12579953-B2 | Display apparatus, control module thereof and drive method therefor | BEIJING BOE DISPLAY TECHNOLOGY CO., LTD. (CN) | 2026-03-17 | — | — | US | claimed |
| US-20260018143-A1 | DISPLAY APPARATUS, CONTROL MODULE THEREOF AND DRIVE METHOD THEREFOR | BEIJING BOE DISPLAY TECH CO (CN) | 2026-01-15 | — | — | US | claimed |
| EP-3903445-B1 | METHOD AND SYSTEM FOR ELECTRONIC VOTING | ORANGE (FR) | 2025-08-27 | — | — | EP | claimed |
| EP-4249162-B1 | LASER PROCESSING METHOD, LASER PROCESSING MACHINE, AND PROCESSING PROGRAM CREATION DEVICE | AMADA CO LTD (JP) | 2025-05-28 | — | — | EP | claimed |
| CN-119930613-A | Organic electroluminescent material based on pyrazine derivatives and preparation method and application thereof | 海南师范大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119880490-A | Floor sweeping robot detection method | 苏州品嘉电子科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119780815-A | Radio frequency chip test station calibration scheme | 芯云纵横半导体(上海)有限公司 | 2025-04-08 | — | — | CN | claimed |
| US-20250092360-A1 | METHODS AND COMPOSITIONS FOR GENERATING SOMATOSTATIN+ INTERNEURONS FROM HUMAN FOREBRAIN NEURAL PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2025-03-20 | — | — | US | claimed |
| CN-119629344-A | Generalized JPEG gray scale image compression module based on FPGA | 北京遥测技术研究所 | 2025-03-14 | — | — | CN | claimed |
| CN-115766967-A | Data processing method for high-definition image transmission | 中邮通建设咨询有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-115464723-A | Parallel type synchronous prefabricated plywood production line and production method | 西南林业大学 | 2022-12-13 | — | — | CN | claimed |
| CN-110187883-B | Register pair allocation method and storage medium for instruction target operand | 湖南科技大学 | 2022-12-06 | — | — | CN | claimed |
| EP-4090563-A1 | VEHICLE MOTION MANAGEMENT BASED ON TORQUE REQUEST WITH SPEED LIMIT | VOLVO TRUCK CORPORATION (SE) | 2022-11-23 | — | — | EP | claimed |
| CN-115320329-A | Method, system and medium for calculating area and energy of light spot of sunlight incident on human body | 上海普法芬电子科技有限公司 | 2022-11-11 | — | — | CN | claimed |
| WO-2022228435-A1 | LOCKED ROTOR DETECTION METHOD AND APPARATUS FOR SCREEN-PRESSING PREVENTION IN PHOTO-CURING 3D PRINTING | 深圳市创必得科技有限公司 | 2022-11-03 | — | — | WO | claimed |
| CN-114945496-A | Vehicle motion management based on torque requests with speed limits | 沃尔沃卡车集团 | 2022-08-26 | — | — | CN | claimed |
| EP-3750015-B1 | AUTOMATIC MACHINE FOR THE PRODUCTION OR PACKAGING OF SMOKING, SANITARY, FOODSTUFF, OR PHARMACEUTICAL PRODUCTS AND CORRESPONDING CONTROL METHOD | GD SPA (IT) | 2022-08-17 | — | — | EP | claimed |
| WO-2022160545-A1 | LIGHT HOMOGENIZATION AND OPTIMAL COMPENSATION METHOD AND APPARATUS FOR LCD PHOTO-CURING 3D PRINTING | 深圳市创必得科技有限公司 | 2022-08-04 | — | — | WO | claimed |
| CN-217114906-U | Conveniently connect and insert subassembly of connecing of taking communication and power supply function | 福建时代星云科技有限公司 | 2022-08-02 | — | — | CN | claimed |