Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50743 | 0.83 | PARP1 (0.46) | CCNA2CDK2CCNA1ALDH1A1KMT2A | |
| SCHEMBL13653826 | 0.82 | SCN9A (0.40) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| SCHEMBL13286195 | 0.82 | KIF11 (0.41) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| SCHEMBL18661421 | 0.82 | CHEK2 (0.42) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| SCHEMBL50237 | 0.81 | PARP1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4829833 | 0.81 | SCN9A (0.53) | SCN9A | |
| SCHEMBL13965805 | 0.80 | CCNA2 (0.36) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| SCHEMBL1173615 | 0.80 | KIF11 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL50553 | 0.79 | NR1I2 (0.44) | SCN9A | |
| SCHEMBL646981 | 0.78 | MAPKAPK2 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |