Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283689 | 0.86 | MAOB (0.50) | IGF1RALOX5HPGDALDH1A1XBP1 | |
| SCHEMBL4197723 | 0.77 | MAPK14 (0.44) | IGF1RALOX5HPGDALDH1A1XBP1 | |
| SCHEMBL4203744 | 0.77 | MAPK14 (0.42) | IGF1RALOX5HPGDALDH1A1XBP1 | |
| SCHEMBL14653628 | 0.74 | PIM1 (0.50) | KMT2ATSHRSMN1; SMN2TP53KDM4E | |
| SCHEMBL379281 | 0.72 | MAOB (0.67) | ALOX5MAOBMRGPRX4 | |
| SCHEMBL2137838 | 0.70 | MRGPRX4 (0.69) | ALOX5MAOBMRGPRX4 | |
| SCHEMBL12635690 | 0.70 | MAOB (0.60) | MAOBTP53POLBMRGPRX4 | |
| SCHEMBL8227293 | 0.69 | MAOB (0.62) | ALOX5ALDH1A1KMT2AMAOBKDM4E | |
| SCHEMBL4074309 | 0.68 | S1PR1 (0.41) | ALOX5KMT2ASMN1; SMN2MAOB | |
| SCHEMBL4073057 | 0.68 | MAOB (0.41) | ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091152-A1 | TRIAZOLOPYRIDINE COMPOUNDS | PFIZER LIMITED (GB) | 2007-08-16 | — | — | WO | disclosed |