Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 4/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.64 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | SOD1 | P00441 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379281 | 0.98 | MAOB (0.67) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL16346074 | 0.94 | GSTP1 (0.66) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL7346174 | 0.91 | MRGPRX4 (0.64) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL6099245 | 0.90 | MRGPRX4 (0.58) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL1956583 | 0.90 | MRGPRX4 (0.58) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL30426715 | 0.90 | MAOB (0.68) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL3786472 | 0.90 | MAOB (0.68) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL2570119 | 0.90 | MAOB (0.65) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL3687040 | 0.88 | MRGPRX4 (0.57) | MRGPRX4MAOBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL9405631 | 0.88 | MAOB (0.71) | MRGPRX4MAOBNR4A2BCHEGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478836-B | Benzofuran compounds and its preparation, purposes | 上海交通大学 | 2017-06-13 | — | — | CN | disclosed |
| US-8242278-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-1473286-B1 | PROCESS FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI | 2009-08-27 | — | — | US | disclosed |
| US-7554000-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| CN-1303043-C | Process for producing biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2007-03-07 | — | — | CN | disclosed |
| CN-1642879-A | Process for preparing diaryl compounds | SUMITOMO CHEMICAL CO (JP) | 2005-07-20 | — | — | CN | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | MRGPRX4 2689/4885MAOB 30/4885NR4A2 2875/4885 |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | MRGPRX4 2689/4885MAOB 30/4885NR4A2 2875/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | MRGPRX4 2689/4885MAOB 30/4885NR4A2 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.