Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466287 | 0.86 | L3MBTL1 (0.55) | NR1H2NR1H3CA12CA9L3MBTL1 | |
| SCHEMBL30083343 | 0.86 | L3MBTL1 (0.55) | NR1H2NR1H3CA12CA9L3MBTL1 | |
| SCHEMBL12960975 | 0.78 | NR1H2 (0.57) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL15231418 | 0.78 | NR1H2 (0.58) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL30777135 | 0.77 | NR1H2 (0.54) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL27868876 | 0.77 | NR1H2 (0.54) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL24893884 | 0.77 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL31370431 | 0.77 | NR1H2 (0.66) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL5519418 | 0.77 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL28006421 | 0.76 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098356-A1 | CONGENERS OF MILNACIPRAN AS MONOAMINE RE-UPTAKE | NEUROCRINE BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |