Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.74 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4875467 | 0.99 | AOC3 (0.73) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14019640 | 0.94 | AOC3 (0.73) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL4876136 | 0.93 | AOC3 (0.73) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4986255 | 0.93 | AOC3 (0.63) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3943198 | 0.93 | AOC3 (0.74) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14417438 | 0.93 | AOC3 (0.63) | AOC3CA1CA2 | |
| SCHEMBL4874225 | 0.92 | AOC3 (0.70) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL3939144 | 0.92 | AOC3 (0.74) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL4867107 | 0.92 | AOC3 (0.64) | AOC3CA1CA2 | |
| SCHEMBL14365397 | 0.91 | AOC3 (0.67) | AOC3PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608365-B1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | R TECH UENO LTD (JP) | 2013-10-02 | — | — | EP | claimed |
| EP-1737450-B1 | AQUEOUS COMPOSITION COMPRISING A THIAZOLE DERIVATIVE | R TECH UENO LTD (JP) | 2009-09-16 | — | — | EP | claimed |
| US-7442715-B2 | Thiazole derivatives | ASTELLAS PHARMA INC. (JP) | 2008-10-28 | — | — | US | claimed |
| US-20080119462-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2008-05-22 | — | — | US | claimed |
| US-20070208068-A1 | Aqueous Composition Comprising Thiazole Derivative | R-TECH UENO, LTD. & ASTELLAS PHARMA INC. | 2007-09-06 | — | — | US | claimed |
| US-20060276521-A1 | Thiazole derivatives | ASTELLAS PHARMA INC. (JP) | 2006-12-07 | — | — | US | claimed |
| US-7125901-B2 | Thiazole derivatives | ASTELLAS PHARMA INC. (JP) | 2006-10-24 | — | — | US | claimed |
| US-20060229346-A1 | Method for treating vascular hyperpermeable disease | SUCAMPO AG (CH) | 2006-10-12 | — | — | US | claimed |
| EP-1608365-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | Sucampo AG (CH) | 2005-12-28 | — | — | EP | claimed |
| US-20040259923-A1 | Compound useful as cellular adhesion protein and as antiedemic agent | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-12-23 | — | — | US | claimed |
| WO-2004087138-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2004-10-14 | — | — | WO | claimed |
| US-10576148-B2 | Use of VAP-1 inhibitors for treating fibrotic conditions | BIOTIE THERAPIES CORP. (FI) | 2020-03-03 | — | — | US | disclosed |
| US-20180071388-A1 | USE OF VAP-1 INHIBITORS FOR TREATING FIBROTIC CONDITIONS | BIOTIE THERAPIES CORP. (FI) | 2018-03-15 | — | — | US | disclosed |
| EP-2475387-B1 | VAP-1 INHIBITORS FOR USE IN TREATING FIBROTIC CONDITIONS | BIOTIE THERAPIES CORP (FI) | 2017-11-01 | — | — | EP | disclosed |
| US-9795671-B2 | Use of VAP-1 inhibitors for treating fibrotic conditions | BIOTIE THERAPIES CORP. (FI) | 2017-10-24 | — | — | US | disclosed |
| EP-1587800-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | Astellas Pharma Inc. (JP) | 2005-10-26 | — | — | EP | disclosed |
| WO-2005089755-A1 | AQUEOUS COMPOSITION COMPRISING THIAZOLE DERIVATIVE | R-TECH UENO, LTD. (JP) | 2005-09-29 | — | — | WO | disclosed |
| US-20040259923-A1 | Compound useful as cellular adhesion protein and as antiedemic agent | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-12-23 | — | — | US | disclosed |
| WO-2004087138-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004067521-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119462-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | VCAM1, ICAM1, VAPB | AOC3 202/4885PIK3CD 4600/4885PIK3CA 4444/4885 |
| US-20060276521-A1 | Thiazole derivatives | VCAM1, ICAM1, TXNL1 | AOC3 782/4885PIK3CD 4519/4885PIK3CA 4514/4885 |
| US-20070208068-A1 | Aqueous Composition Comprising Thiazole Derivative | SLC5A1, SLC5A2, SLC10A1 | AOC3 3576/4885PIK3CD 2571/4885PIK3CA 2241/4885 |
| US-20060229346-A1 | Method for treating vascular hyperpermeable disease | VCAM1, VAPB, ICAM1 | AOC3 85/4885PIK3CD 4683/4885PIK3CA 4321/4885 |
| US-20040259923-A1 | Compound useful as cellular adhesion protein and as antiedemic agent | VCAM1, ICAM1, VAPB | AOC3 590/4885PIK3CD 3966/4885PIK3CA 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.