Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 9/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431134 | 0.87 | AKT1 (0.46) | AKT1HDAC8DPP4DPP7MC4R | |
| SCHEMBL14435277 | 0.84 | AKT1 (0.46) | AKT1HDAC8DPP4DPP7MC4R | |
| SCHEMBL14435276 | 0.84 | AKT1 (0.46) | AKT1HDAC8DPP4DPP7MC4R | |
| SCHEMBL14435254 | 0.80 | AKT1 (0.44) | AKT1HDAC8DPP4DPP7MC4R | |
| SCHEMBL14435266 | 0.80 | AKT1 (0.44) | AKT1HDAC8DPP4DPP7MC4R | |
| SCHEMBL14435595 | 0.79 | AKT1 (0.45) | AKT1DPP4DPP7MC4RFAP | |
| SCHEMBL14435257 | 0.78 | AKT1 (0.45) | AKT1DPP4DPP7MC4RFAP | |
| SCHEMBL14435563 | 0.77 | HDAC8 (0.48) | AKT1HDAC8DPP4MC4R | |
| SCHEMBL14435256 | 0.77 | AKT1 (0.44) | AKT1DPP4DPP7MC4ROPRD1 | |
| Hydrochloric Acid SCHEMBL4678422 | 0.74 | AKT1 (0.48) | AKT1DPP4DPP7MC4RFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |