SCHEMBL14435613 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	DPP4	P27487	7/20	0.44

▸	DPP7	Q9UHL4	7/20	0.44

▸	AKT1	P31749	8/20	0.43

▸	MC4R	P32245	1/20	0.39

▸	MC3R	P41968	1/20	0.39

▸	MC1R	Q01726	1/20	0.39

▸	FAP	Q12884	1/20	0.37

▸	DPP8	Q6V1X1	1/20	0.37

▸	DPP9	Q86TI2	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14435265	0.90	AKT1 (0.43)	DPP4DPP7AKT1MC4RMC3R
SCHEMBL14435259	0.90	AKT1 (0.43)	DPP4DPP7AKT1MC4RMC3R
SCHEMBL14435266	0.85	AKT1 (0.44)	DPP4DPP7AKT1MC4RMC3R
SCHEMBL14435254	0.85	AKT1 (0.44)	DPP4DPP7AKT1MC4RMC3R
SCHEMBL14435256	0.85	AKT1 (0.44)	DPP4DPP7AKT1MC4RMC3R
SCHEMBL12713217	0.82	CNR1 (0.42)	DPP4MC4R
SCHEMBL14435280	0.81	MC4R (0.41)	MC4RMC3R
SCHEMBL14435277	0.80	AKT1 (0.46)	DPP4DPP7AKT1MC4RMC3R
SCHEMBL14435276	0.80	AKT1 (0.46)	DPP4DPP7AKT1MC4RMC3R
SCHEMBL12737875	0.79	HTR6 (0.38)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007096186-A1	SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS	SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH)	2007-08-30	—	—	WO	disclosed