Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437745 | 0.89 | UTS2R (0.59) | UTS2RMEN1KMT2A | |
| SCHEMBL12437766 | 0.85 | HRH3 (0.59) | UTS2RMCHR1HRH3MEN1KMT2A | |
| SCHEMBL14435668 | 0.82 | SLC5A7 (0.50) | HRH3MEN1KMT2A | |
| SCHEMBL12437753 | 0.79 | UTS2R (0.58) | UTS2RHRH3MEN1KMT2A | |
| SCHEMBL12437572 | 0.75 | TMEM97 (0.61) | MCHR1DRD4HRH3MEN1KMT2A | |
| SCHEMBL12437763 | 0.75 | UTS2R (0.51) | UTS2RDRD4MEN1KMT2A | |
| SCHEMBL12437573 | 0.75 | KMT2A (0.67) | MCHR1DRD4MEN1KMT2A | |
| SCHEMBL16972253 | 0.74 | BRD4 (0.51) | HRH3POLB | |
| SCHEMBL2214246 | 0.74 | EPHX2 (0.55) | UTS2R | |
| SCHEMBL12437764 | 0.74 | UTS2R (0.64) | UTS2RMCHR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098086-A2 | HYDROXYPIPERIDINE DERIVATIVES AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2007-08-30 | — | — | WO | disclosed |