Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 3/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | MC1R | Q01726 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437336 | 0.90 | SLC5A7 (0.50) | SLC5A7DRD2DRD3MEN1KMT2A | |
| SCHEMBL12437957 | 0.87 | SLC5A7 (0.51) | SLC5A7DRD2DRD3MEN1KMT2A | |
| SCHEMBL12437334 | 0.86 | OPRM1 (0.61) | DRD2DRD3MEN1KMT2AOPRM1 | |
| SCHEMBL12437365 | 0.85 | MEN1 (0.61) | SLC5A7DRD2DRD3MEN1KMT2A | |
| SCHEMBL12437948 | 0.83 | SLC5A7 (0.56) | SLC5A7MEN1KMT2AALDH1A1CCR3 | |
| SCHEMBL12437341 | 0.83 | OPRM1 (0.61) | MEN1KMT2AOPRM1OPRD1ALDH1A1 | |
| SCHEMBL12437947 | 0.83 | SLC5A7 (0.56) | SLC5A7MEN1KMT2AALDH1A1CCR3 | |
| SCHEMBL12437596 | 0.82 | HRH3 (0.61) | MEN1KMT2AOPRM1OPRD1ALDH1A1 | |
| SCHEMBL14435679 | 0.82 | UTS2R (0.47) | MEN1KMT2AHRH3 | |
| SCHEMBL12437349 | 0.81 | SLC5A7 (0.53) | SLC5A7DRD2DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098086-A2 | HYDROXYPIPERIDINE DERIVATIVES AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2007-08-30 | — | — | WO | disclosed |