Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 8/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 6/20 | 0.41 |
| ▸ | CALCA | P06881 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | UGCG | Q16739 | 3/20 | 0.38 |
| ▸ | PYGL | P06737 | 2/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435993 | 1.00 | CCR1 (0.43) | CCR1CYP51A1CALCACYP3A4UGCG | |
| SCHEMBL14436000 | 0.90 | CCR1 (0.42) | CCR1CYP51A1CALCACYP3A4UGCG | |
| SCHEMBL14435259 | 0.88 | AKT1 (0.43) | MC4R | |
| SCHEMBL14435265 | 0.88 | AKT1 (0.43) | MC4R | |
| SCHEMBL14435994 | 0.83 | CCR1 (0.42) | CCR1CYP51A1CALCACYP3A4UGCG | |
| SCHEMBL14436005 | 0.83 | CCR1 (0.42) | CCR1CYP51A1CALCACYP3A4UGCG | |
| SCHEMBL14435266 | 0.82 | AKT1 (0.44) | MC4R | |
| SCHEMBL14435254 | 0.82 | AKT1 (0.44) | MC4R | |
| SCHEMBL13002965 | 0.79 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL14435280 | 0.79 | MC4R (0.41) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |