Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.96 |
| ▸ | TSHR | P16473 | 3/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.96 |
| ▸ | TP53 | P04637 | 2/20 | 0.96 |
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | HBB | P68871 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940306 | 1.00 | TDP1 (0.96) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL29539970 | 1.00 | TDP1 (0.96) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL752490 | 1.00 | TDP1 (0.96) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL29155111 | 0.98 | TDP1 (0.93) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL29441860 | 0.98 | TDP1 (1.00) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| Lithium SCHEMBL30739531 | 0.98 | TDP1 (0.93) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL9558913 | 0.98 | TDP1 (1.00) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL1756337 | 0.98 | TDP1 (1.00) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL29155112 | 0.98 | TDP1 (0.93) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL136697 | 0.98 | TDP1 (1.00) | TDP1MAPK1CYP3A4SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070198063-A1 | Electrical devices and anti-scarring drug combinations | HUNTER WILLIAM L | 2007-08-23 | — | — | US | disclosed |
| US-20070198063-A1 | Electrical devices and anti-scarring drug combinations | HUNTER WILLIAM L | 2007-08-23 | — | — | US | disclosed |