Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 2/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.32 |
| ▸ | STK10 | O94804 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14437310 | 0.91 | CISD1 (0.48) | CISD1MEN1XDHKMT2ACCNC | |
| SCHEMBL5505342 | 0.91 | CISD1 (0.48) | CISD1MEN1XDHKMT2ACCNC | |
| SCHEMBL5505339 | 0.91 | CISD1 (0.48) | CISD1MEN1XDHKMT2ACCNC | |
| SCHEMBL5502498 | 0.88 | CISD1 (0.35) | CISD1CCNCCDK8CSNK2A2CSNK2A1 | |
| SCHEMBL14437295 | 0.87 | CISD1 (0.45) | CISD1MEN1XDHKMT2AALOX5 | |
| SCHEMBL14437302 | 0.82 | CISD1 (0.44) | CISD1MEN1XDHKMT2ACCNC | |
| SCHEMBL3864350 | 0.79 | CISD1 (0.48) | CISD1MEN1XDHKMT2AALOX5 | |
| SCHEMBL3868935 | 0.79 | CISD1 (0.48) | CISD1MEN1XDHKMT2AALOX5 | |
| SCHEMBL3864349 | 0.79 | CISD1 (0.48) | CISD1MEN1XDHKMT2AALOX5 | |
| SCHEMBL14452267 | 0.79 | CISD1 (0.46) | CISD1MEN1XDHKMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253285-B2 | Thiazolinone 4-monosubstituted quinolines | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253285-B2 | Thiazolinone 4-monosubstituted quinolines | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |