Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639002 | 0.86 | TAAR1 (0.45) | HDAC1HDAC2KAT2BTAAR1HDAC3 | |
| SCHEMBL15233019 | 0.82 | HDAC1 (0.41) | HDAC1HDAC2KAT2BHDAC3HDAC8 | |
| Benzene SCHEMBL27800821 | 0.78 | TRPA1 (0.43) | HDAC1HDAC2KAT2BHDAC3HDAC8 | |
| SCHEMBL13437571 | 0.78 | TRPA1 (0.43) | HDAC1HDAC2KAT2BHDAC3HDAC8 | |
| SCHEMBL22504876 | 0.78 | TRPA1 (0.43) | HDAC1HDAC2KAT2BHDAC3HDAC8 | |
| SCHEMBL18804475 | 0.77 | GRIN2B (0.39) | HDAC1HDAC2KAT2BTAAR1HDAC3 | |
| SCHEMBL18804472 | 0.75 | GRIN2B (0.38) | HDAC1HDAC2TAAR1HDAC3HDAC8 | |
| SCHEMBL14189703 | 0.75 | HDAC3 (0.45) | HDAC1HDAC2KAT2BHDAC3HDAC8 | |
| SCHEMBL12885408 | 0.73 | TRPA1 (0.39) | TAAR1GRIN2BGAAABCC4LMNA | |
| SCHEMBL24437513 | 0.73 | HRH3 (0.56) | HDAC1HDAC2TAAR1HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7880037-B2 | Phosphonium supported triphenylphosphine; for controlling solubility of a molecule; oxidation of Cinnamyl Alcohol using above catalyst system | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-02-01 | — | — | US | disclosed |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | PI4K2A, PIP4K2A, PI4K2B | HDAC1 2102/4885HDAC2 1637/4885KAT2B 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.