Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611355 | 0.83 | PTPN1 (0.52) | PTPN1PTPRCCDC25BKDM4EGAA | |
| SCHEMBL4303531 | 0.78 | PTPN1 (0.68) | PTPN1PTPRCCDC25BPOLBMEN1 | |
| SCHEMBL13611357 | 0.77 | HDAC3 (0.47) | PTPN1PTPRCCDC25BKDM4EMAPT | |
| SCHEMBL13624811 | 0.72 | PTPN1 (0.47) | PTPN1PTPRCCDC25BALDH1A1TOP2A | |
| SCHEMBL4298282 | 0.72 | PTPN1 (0.67) | PTPN1PTPRCCDC25BKDM4EMAPT | |
| SCHEMBL4294827 | 0.71 | PTPN1 (0.58) | PTPN1PTPRCCDC25BMAPTRAB9A | |
| SCHEMBL8583861 | 0.71 | PTPN1 (0.65) | PTPN1PTPRCCDC25BKDM4EMAPT | |
| SCHEMBL5596353 | 0.71 | PTPN1 (0.68) | PTPN1PTPRCCDC25BKDM4EMAPT | |
| SCHEMBL7239673 | 0.70 | PTPN1 (0.56) | PTPN1PTPRCCDC25BALDH1A1LTB4R | |
| SCHEMBL4291302 | 0.70 | PTPN1 (0.88) | PTPN1PTPRCCDC25BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |