SCHEMBL14439648

SCHEMBL14439648

CCNC(=O)COCC(=O)NCCOCCOCCN=[N+]=[N-]

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ TTR P02766 1/20 0.34
▸ GLP1R P43220 5/20 0.33
▸ TSHR P16473 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18886307 0.93 CRBN (0.38) CRBNMEN1KMT2ATTR
SCHEMBL15284774 0.87 CRBN (0.36) CRBNMEN1KMT2ATTRGLP1R
SCHEMBL14129583 0.87 CRBN (0.36) CRBNMEN1KMT2ATTRGLP1R
SCHEMBL14787951 0.87 CRBN (0.36) CRBNMEN1KMT2ATTRGLP1R
SCHEMBL22957224 0.85 MEN1 (0.41) CRBNMEN1KMT2ATTRRECQL
SCHEMBL13695954 0.85 MEN1 (0.41) CRBNMEN1KMT2ATTRRECQL
SCHEMBL14439651 0.84 CRBN (0.35) CRBNMEN1KMT2ATTRGLP1R
SCHEMBL18385066 0.84 GLP1R (0.38) CRBNMEN1KMT2ATTRGLP1R
SCHEMBL13695963 0.82 CASP2 (0.41) CRBNMEN1KMT2ATTR
SCHEMBL30377114 0.82 CASP2 (0.41) CRBNMEN1KMT2ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256259-B2 Methods for ligation of molecules to surfaces WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-08-14 — — US disclosed
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