Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.70 |
| ▸ | TNF | P01375 | 9/20 | 0.65 |
| ▸ | PDE4A | P27815 | 3/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439748 | 0.88 | UTS2R (0.66) | UTS2RTNFPDE4APDE4BPDE4C | |
| SCHEMBL1472430 | 0.85 | UTS2R (0.80) | UTS2R | |
| SCHEMBL1472426 | 0.85 | UTS2R (0.80) | UTS2R | |
| SCHEMBL1472830 | 0.83 | UTS2R (1.00) | UTS2R | |
| SCHEMBL9884538 | 0.83 | UTS2R (1.00) | UTS2R | |
| SCHEMBL12828607 | 0.83 | UTS2R (1.00) | UTS2R | |
| SCHEMBL1472607 | 0.83 | UTS2R (1.00) | UTS2R | |
| SCHEMBL9884535 | 0.82 | TNF (0.66) | UTS2RTNFPDE4APDE4BPDE4C | |
| SCHEMBL8239617 | 0.82 | TNF (0.66) | UTS2RTNFPDE4APDE4BPDE4C | |
| SCHEMBL1472310 | 0.81 | UTS2R (0.96) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536174-B2 | Urotensin II receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2013-09-17 | — | — | US | disclosed |
| US-20070191391-A1 | Urotensin II receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191391-A1 | Urotensin II receptor antagonists | UTS2R, PLAUR, BDKRB2 | UTS2R 1/4885TNF 1287/4885PDE4A 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.