Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441290 | 0.81 | MAPT (0.49) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL3829799 | 0.81 | MAPT (0.49) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL22417606 | 0.77 | GAA (0.46) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL397465 | 0.77 | GAA (0.46) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL26262448 | 0.77 | GAA (0.46) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL28253303 | 0.75 | GAA (0.44) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL11923533 | 0.71 | GAA (0.41) | GAAMAPTEPHX2BRD4CREBBP | |
| SCHEMBL30681543 | 0.70 | PNMT (0.56) | GAAMAPTBRD4CREBBPAR | |
| SCHEMBL13306140 | 0.66 | GAA (0.46) | GAAMAPTP2RX7BRD4CREBBP | |
| SCHEMBL28533908 | 0.66 | GAA (0.46) | GAAMAPTP2RX7BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203224-A1 | SMALL-MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-08-30 | — | — | US | disclosed |