Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456739 | 0.91 | GRM2 (0.51) | GRM2HRH3CYP2D6HRH1 | |
| SCHEMBL5455754 | 0.82 | HRH3 (0.45) | HRH3CYP2D6HRH1 | |
| SCHEMBL5452213 | 0.82 | MAOA (0.50) | HRH3CYP2D6HRH1 | |
| SCHEMBL8115184 | 0.74 | GRM2 (0.80) | GRM2 | |
| SCHEMBL8114677 | 0.73 | GRM2 (0.85) | GRM2 | |
| SCHEMBL2822970 | 0.72 | GRM2 (0.70) | GRM2 | |
| SCHEMBL2826289 | 0.72 | GRM2 (0.70) | GRM2 | |
| SCHEMBL8114539 | 0.71 | GRM2 (0.64) | GRM2 | |
| Hydrochloric Acid SCHEMBL8115132 | 0.70 | GRM2 (0.62) | GRM2 | |
| SCHEMBL9447636 | 0.70 | F10 (0.53) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | GRM2 66/4885HRH3 38/4885CYP2D6 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.