Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ADA | P00813 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737904 | 0.93 | ADORA2A (0.53) | ADORA2ALMNAMTORTHRBMDM2 | |
| SCHEMBL6730328 | 0.93 | ADORA2A (0.53) | ADORA2ALMNAMTORTHRBMDM2 | |
| SCHEMBL14440600 | 0.83 | ADORA2A (0.47) | ADORA2AADORA3 | |
| SCHEMBL14440914 | 0.82 | PNP (0.45) | ADORA2ALMNAMTORTHRBMDM2 | |
| SCHEMBL12154572 | 0.82 | ADORA2A (0.53) | ADORA2AADASLC29A1PDE4DPDE3A | |
| SCHEMBL474846 | 0.82 | ADORA2A (0.53) | ADORA2AADASLC29A1PDE4DPDE3A | |
| SCHEMBL12150880 | 0.82 | ADORA2A (0.53) | ADORA2AADASLC29A1PDE4DPDE3A | |
| SCHEMBL12031227 | 0.82 | ADORA2A (0.53) | ADORA2AADASLC29A1PDE4DPDE3A | |
| SCHEMBL6729928 | 0.82 | LMNA (0.58) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL1737343 | 0.82 | LMNA (0.58) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | ADORA2A 566/4885LMNA 1658/4885MTOR 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.