Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BDNF | P23560 | 3/20 | 0.32 |
| ▸ | PTN | P21246 | 2/20 | 0.32 |
| ▸ | MDK | P21741 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BMP2 | P12643 | 1/20 | 0.31 |
| ▸ | VEGFA | P15692 | 1/20 | 0.31 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.31 |
| ▸ | SHH | Q15465 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444723 | 0.82 | LMNA (0.34) | LGALS3CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL14444736 | 0.76 | HPSE (0.33) | VEGFACXCL12 | |
| SCHEMBL26445659 | 0.72 | CYP3A4 (0.55) | MAPK1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL18102370 | 0.72 | CYP3A4 (0.55) | MAPK1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL16393109 | 0.72 | CYP3A4 (0.55) | MAPK1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL25098517 | 0.72 | CYP3A4 (0.55) | MAPK1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL24922818 | 0.72 | CYP3A4 (0.55) | MAPK1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL29772234 | 0.72 | CYP3A4 (0.55) | MAPK1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL22606447 | 0.72 | CYP3A4 (0.55) | MAPK1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL23794931 | 0.71 | CYP3A4 (0.54) | MAPK1LGALS8LGALS3LGALS4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244830-B2 | Glycopolymers and free radical polymerization methods | EMORY UNIVERSITY (US) | 2007-07-17 | — | — | US | disclosed |