Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.69 |
| ▸ | CCR2 | P41597 | 15/20 | 0.64 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367011 | 0.91 | BCHE (0.57) | TACR1CCR2 | |
| SCHEMBL14445038 | 0.89 | CCR2 (0.62) | TACR1CCR2CCR5 | |
| SCHEMBL14445128 | 0.85 | CCR2 (0.51) | TACR1CCR2CCR5 | |
| SCHEMBL14445247 | 0.84 | CCR2 (0.58) | TACR1CCR2 | |
| SCHEMBL14445286 | 0.81 | CCR2 (0.58) | TACR1CCR2 | |
| SCHEMBL14445123 | 0.80 | TACR1 (0.65) | TACR1CCR2CCR5 | |
| SCHEMBL14445036 | 0.79 | CCR2 (0.61) | TACR1CCR2CCR5 | |
| SCHEMBL5515398 | 0.79 | TACR1 (0.62) | TACR1CCR2CCR5 | |
| SCHEMBL5515392 | 0.79 | TACR1 (0.62) | TACR1CCR2CCR5 | |
| SCHEMBL8911293 | 0.78 | TACR1 (0.72) | TACR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |