SCHEMBL1444530

SCHEMBL1444530

C=CCc1ccccc1Oc1ccc(C#N)c(C#N)c1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AR P10275 11/20 0.50
MAOB P27338 2/20 0.44
MAOA P21397 1/20 0.43
CYP19A1 P11511 1/20 0.43
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
SLC6A4 P31645 1/20 0.41
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4174164 0.88 AR (0.60) ARSLC6A4
SCHEMBL4171296 0.85 AR (0.72) AR
SCHEMBL20964552 0.84 AR (0.56) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL13327517 0.81 AR (0.53) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL21270043 0.81 AR (0.71) ARMAOBCYP19A1ALDH1A1HPGD
SCHEMBL9352980 0.80 HRH1 (0.47) ALDH1A1SLC6A4
SCHEMBL1940627 0.80 AR (0.57) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL20510971 0.79 AR (0.50) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL8981215 0.79 SLC6A2 (0.45) ALDH1A1SLC6A4
SCHEMBL29106729 0.78 HRH1 (0.46) ALDH1A1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN claimed
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US claimed
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2020-04-30 US claimed
EP-3601215-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M Innovative Properties Company (US) 2020-02-05 EP claimed
WO-2018175025-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-09-27 WO claimed
US-6933402-B2 Phthalocyanines with peripheral siloxane substitution THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2005-08-23 US claimed
US-20030092907-A1 Phthalocyanines with peripheral siloxane substitution NAVY,U.S.A. AS REPRESENTED BY, THE SECRETARY OF THE 2003-05-15 US claimed
US-6498249-B1 Phthalocyanines with peripheral siloxane substitution THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2002-12-24 US claimed
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN disclosed
CN-109071808-B Bisphenol M bisphthalonitrile ether resin blends containing filler and articles 3M创新有限公司 2022-12-09 CN disclosed
US-11499032-B2 Curable fluoropolymer compositions comprising a compound containing a phthalonitrile and an olefinic bond and cured articles therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-15 US disclosed
US-20220251338-A1 Curable Fluoropolymer Compositions Comprising a Compound Containing a Phthalonitrile and an Olefinic Bond and Cured Articles Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2022-08-11 US disclosed
US-20220251338-A1 Curable Fluoropolymer Compositions Comprising a Compound Containing a Phthalonitrile and an Olefinic Bond and Cured Articles Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2022-08-11 US disclosed
EP-4017913-A1 CURABLE FLUOROPOLYMER COMPOSITIONS COMPRISING A COMPOUND CONTAINING A PHTHALONITRILE AND AN OLEFINIC BOND AND CURED ARTICLES THEREFROM 3M Innovative Properties Company (US) 2022-06-29 EP disclosed
WO-2011037619-A1 POLYMERIC DYE FOR OPTICAL POWER LIMITING OXAZOGEN, INC. (US) 2011-03-31 WO disclosed
US-7550586-B2 Phthalocyanines with peripheral siloxane substitution THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-06-23 US disclosed
US-20050200803-A1 Phthalocyanines with peripheral siloxane substitution THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY 2005-09-15 US disclosed
US-6933402-B2 Phthalocyanines with peripheral siloxane substitution THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2005-08-23 US disclosed
US-20030092907-A1 Phthalocyanines with peripheral siloxane substitution NAVY,U.S.A. AS REPRESENTED BY, THE SECRETARY OF THE 2003-05-15 US disclosed
US-6498249-B1 Phthalocyanines with peripheral siloxane substitution THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2002-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES PNN, RPN1, DCXR AR 2001/4885MAOB 4087/4885MAOA 3839/4885
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles PNN, RPN1, DCXR AR 2001/4885MAOB 4087/4885MAOA 3839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.