RPN1

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 · P04843 · RPN1 on Sugi Atlas →

0 patent compounds predicted against RPN1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to RPN1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision PHASE3COMPLETED
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia PHASE2COMPLETED
A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001 PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa PHASE1COMPLETED
MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby) PHASE1COMPLETED
SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects PHASE1COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
InsightRP2 Registry nanRECRUITING
Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial nanCOMPLETED
Biomarker for Hurler Disease (BioHurler) nanWITHDRAWN
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
The Natural History of Alpha-Mannosidosis nanCOMPLETED
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
Effects of Subtenon-injected Autologous Platelet-rich Plasma on Visual Functions in Eyes With Retinitis Pigmentosa nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation nanCOMPLETED
Gene Modifiers of Cystic Fibrosis Lung Disease nanACTIVE_NOT_RECRUITING
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes nanRECRUITING
Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study nanUNKNOWN
Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome nanRECRUITING
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING
The Classification and Cause of Leukodystrophies of Unknown Cause nanCOMPLETED
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis nanRECRUITING
Biomarker for Patients With Fabry Disease (BioFabry) nanWITHDRAWN
Glycosylation in Patients With Galactosaemia nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RPN1 binder may also engage these)

ProteinNameSimilarity
E2RQ08 1.000 E2RQ08 →
Q4R4T0 1.000 Q4R4T0 →
Q91YQ5 1.000 Q91YQ5 →
Q5RFB6 1.000 Q5RFB6 →
Q9GMB0 0.997 Q9GMB0 →
P07153 0.995 P07153 →
Q0DJC5 0.981 Q0DJC5 →
F1PCT7 0.977 F1PCT7 →
EMC1 ER membrane protein complex subunit 1 0.976 landscape →
Q3SZI6 0.974 Q3SZI6 →
Q8IYB8 0.974 Q8IYB8 →
Q9CQF9 0.974 Q9CQF9 →
Q6NTR1 0.973 Q6NTR1 →
Q5R9S8 0.973 Q5R9S8 →
Q5R981 0.973 Q5R981 →
A1A4I9 0.973 A1A4I9 →
B9FDT1 0.972 B9FDT1 →
Q9Y312 0.972 Q9Y312 →
Q8N1G2 0.972 Q8N1G2 →
Q5R5N9 0.972 Q5R5N9 →
Q9UJA3 0.972 Q9UJA3 →
COASY Bifunctional coenzyme A synthase 0.972 landscape →
Q6PGY6 0.972 Q6PGY6 →
Q8CCJ3 0.971 Q8CCJ3 →
O00423 0.971 O00423 →
Q9YHB5 0.971 Q9YHB5 →
Q04499 0.971 Q04499 →
Q99LC3 0.971 Q99LC3 →
F4IDS7 0.971 F4IDS7 →
NAT10 RNA cytidine acetyltransferase 0.971 landscape →