Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368225 | 0.86 | MET (0.70) | MET | |
| SCHEMBL14445376 | 0.83 | MET (0.65) | MET | |
| SCHEMBL16042878 | 0.76 | GRM2 (0.52) | MET | |
| SCHEMBL12689580 | 0.76 | MET (0.66) | MET | |
| SCHEMBL1163320 | 0.76 | MET (0.76) | MET | |
| SCHEMBL18418027 | 0.76 | MET (0.67) | MET | |
| SCHEMBL16587101 | 0.76 | MET (0.48) | MET | |
| SCHEMBL22109388 | 0.75 | MET (0.48) | MET | |
| SCHEMBL2569616 | 0.74 | MET (0.66) | MET | |
| SCHEMBL12482456 | 0.73 | MET (0.66) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250417-B2 | Arylmethyl triazolo- and imidazopyrazines as c-Met inhibitors | SUGEN INC. (US) | 2007-07-31 | — | — | US | disclosed |
| US-7250417-B2 | Arylmethyl triazolo- and imidazopyrazines as c-Met inhibitors | SUGEN INC. (US) | 2007-07-31 | — | — | US | disclosed |