Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 14/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GIPR | P48546 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446016 | 0.92 | PPARA (0.51) | PPARGPPARDPPARAGCGRGIPR | |
| SCHEMBL4682098 | 0.88 | PPARG (0.43) | PPARGPPARDPPARAMAPTGCGR | |
| SCHEMBL14445979 | 0.85 | PPARA (0.40) | PPARGPPARDPPARAMAPTGCGR | |
| SCHEMBL14445963 | 0.83 | PPARG (0.38) | PPARGPPARDPPARAMAPT | |
| SCHEMBL5397707 | 0.82 | PPARA (0.45) | PPARGPPARDPPARAMAPTSMN1; SMN2 | |
| SCHEMBL4682081 | 0.81 | MAPT (0.41) | PPARGPPARDPPARAMAPTGCGR | |
| SCHEMBL5415691 | 0.79 | PPARA (0.40) | PPARGPPARDPPARAMAPTGCGR | |
| SCHEMBL5406496 | 0.79 | PPARA (0.41) | PPARGPPARDPPARAGCGRPTGDR2 | |
| SCHEMBL4681928 | 0.78 | MAPT (0.42) | PPARGPPARDPPARAMAPTGCGR | |
| SCHEMBL4682077 | 0.78 | PPARA (0.39) | PPARGPPARDPPARAGCGRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |