Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | PPARD | Q03181 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | GCGR | P47871 | 5/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445976 | 0.91 | PPARA (0.41) | PPARAPPARDPPARGFBP1 | |
| SCHEMBL14446013 | 0.90 | PPARA (0.51) | PPARAPPARDPPARGGCGR | |
| SCHEMBL4682077 | 0.89 | PPARA (0.39) | PPARAPPARDPPARGGCGRABCB11 | |
| SCHEMBL5415691 | 0.89 | PPARA (0.40) | PPARAPPARDPPARGGCGRABCB11 | |
| SCHEMBL14445979 | 0.88 | PPARA (0.40) | PPARAPPARDPPARGGCGRABCB11 | |
| SCHEMBL14445956 | 0.83 | PPARA (0.46) | PPARAPPARDPPARGFBP1 | |
| SCHEMBL4682592 | 0.83 | PPARA (0.41) | PPARAPPARDPPARGABCB11CYP1A2 | |
| SCHEMBL14445987 | 0.81 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL5407750 | 0.81 | PPARD (0.39) | PPARAPPARDPPARGCYP3A4FBP1 | |
| SCHEMBL5397707 | 0.80 | PPARA (0.45) | PPARAPPARDPPARGFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | claimed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |