Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446236 | 0.75 | USP2 (0.37) | POLBUSP2TACR1MEN1KMT2A | |
| SCHEMBL5161190 | 0.71 | HDAC2 (0.36) | USP2TACR1MEN1KMT2A | |
| SCHEMBL14446216 | 0.68 | KDM1A (0.41) | TACR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14446228 | 0.68 | GBA1 (0.38) | TACR1TSHR | |
| SCHEMBL5161755 | 0.68 | GBA1 (0.38) | TACR1TSHR | |
| SCHEMBL5414950 | 0.68 | GBA1 (0.38) | TACR1TSHR | |
| SCHEMBL5162035 | 0.68 | KDM1A (0.41) | TACR1GAAALDH1A1 | |
| SCHEMBL5161943 | 0.68 | KDM1A (0.41) | TACR1GAAALDH1A1 | |
| SCHEMBL5161948 | 0.68 | KDM1A (0.41) | TACR1GAAALDH1A1 | |
| SCHEMBL5162043 | 0.68 | KDM1A (0.41) | TACR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241798-B2 | NK1 antagonists | PFIZER INC. (US) | 2007-07-10 | — | — | US | disclosed |