SCHEMBL14446296

SCHEMBL14446296

FC(F)(F)C1=NCC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28167567 0.62 ALDH1A1 (0.32)
SCHEMBL27934600 0.58
SCHEMBL28592454 0.58
SCHEMBL12197617 0.57
SCHEMBL7458792 0.57
SCHEMBL28412211 0.57
SCHEMBL2044966 0.56
Benzene SCHEMBL28457184 0.54
SCHEMBL10075700 0.53
SCHEMBL13172317 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10028961-B2 Therapeutically active compounds and their methods of use AGIOS PHARMACEUTICALS, INC. (US) 2018-07-24 US disclosed
WO-2017111076-A1 α, β UNSATURATED AMIDE COMPOUND 協和発酵キリン株式会社 2017-06-29 WO disclosed
CN-104418800-B Aryl pyrrole (phonetic) pyridine class compound and application thereof 沈阳中化农药化工研发有限公司 2017-06-16 CN disclosed
US-20170107194-A1 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE SERVIER PHARMACEUTICALS LLC 2017-04-20 US disclosed
US-9579324-B2 Therapeutically active compounds and their methods of use AGIOS PHARMACEUTICALS, INC (US) 2017-02-28 US disclosed
US-20160220572-A1 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE SERVIER PHARMACEUTICALS LLC 2016-08-04 US disclosed
CN-104902751-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902750-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902749-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902752-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104011027-A Use of lonidamine analogs for fertility regulation UNIV KANSAS 2014-08-27 CN disclosed
US-20070167631-A1 Novel herbicides Luthy, Christoph (CH) 2007-07-19 US disclosed
CN-1058841-C Fungicidal oxazolidinones DU PONT (US) 2000-11-29 CN disclosed
CN-1096157-A Antifungal De oxazolidone DU PONT (US) 1994-12-14 CN disclosed
CN-1047079-A FUNGICIDAL OXAZOLIDINONES DU PONT (US) 1990-11-21 CN disclosed