Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446600 | 0.95 | CRHR1 (0.89) | CRHR1 | |
| SCHEMBL14446597 | 0.93 | CRHR1 (0.78) | CRHR1 | |
| SCHEMBL14446585 | 0.92 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL14446590 | 0.91 | CRHR1 (0.85) | CRHR1 | |
| SCHEMBL14446603 | 0.91 | CRHR1 (0.88) | CRHR1 | |
| SCHEMBL14446596 | 0.90 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL14446574 | 0.90 | CRHR1 (0.91) | CRHR1 | |
| SCHEMBL14446581 | 0.89 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL14446586 | 0.89 | CRHR1 (0.77) | CRHR1 | |
| SCHEMBL14446582 | 0.89 | CRHR1 (0.85) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244746-B2 | Imidazolyl derivatives as corticotropin releasing factor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244746-B2 | Imidazolyl derivatives as corticotropin releasing factor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| US-7238699-B2 | Imidazolyl derivatives as corticotropin releasing factor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238699-B2 | Imidazolyl derivatives as corticotropin releasing factor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-03 | — | — | US | disclosed |
| US-7211669-B2 | Imidazolyl derivatives as corticotropin releasing factor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-01 | — | — | US | disclosed |