Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14447296 | 0.93 | PDK2 (0.38) | KDM4ELMNASMN1; SMN2PSMB5PDK2 | |
| SCHEMBL23097346 | 0.93 | PDK2 (0.36) | PDK2AKT1 | |
| SCHEMBL16366413 | 0.90 | PDK2 (0.40) | PDK2 | |
| SCHEMBL21203708 | 0.90 | PDK2 (0.37) | PDK2AKT1 | |
| SCHEMBL17153726 | 0.90 | PDK2 (0.40) | PDK2 | |
| SCHEMBL13153084 | 0.90 | PDK2 (0.36) | PDK2L3MBTL1AKT1HTTNPSR1 | |
| SCHEMBL14447284 | 0.89 | PDK2 (0.32) | ADORA2AADORA1PDK2PDE10ACYP2C19 | |
| SCHEMBL22000746 | 0.89 | PDK2 (0.36) | PDK2AKT1 | |
| SCHEMBL16366322 | 0.89 | PDK2 (0.41) | PDK2 | |
| SCHEMBL24255707 | 0.89 | PDK2 (0.38) | PDK2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9324951-B2 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2016-04-26 | — | — | US | disclosed |
| US-9324951-B2 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2016-04-26 | — | — | US | disclosed |
| US-20150112065-A1 | Pyrazine Derivative, and Light Emitting Element, Display Device, Electronic Device Using the Pyrazine Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2015-04-23 | — | — | US | disclosed |
| US-20150112065-A1 | Pyrazine Derivative, and Light Emitting Element, Display Device, Electronic Device Using the Pyrazine Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2015-04-23 | — | — | US | disclosed |
| US-8920941-B2 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-12-30 | — | — | US | disclosed |
| US-20070161793-A1 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161793-A1 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161793-A1 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | GRIA1, GRIN1, GRIA2 | KDM4E 4164/4885LMNA 3768/4885SMN1; SMN2 4336/4885 |
| US-20150112065-A1 | Pyrazine Derivative, and Light Emitting Element, Display Device, Electronic Device Using the Pyrazine Derivative | GRIA1, GRIN1, GRIA2 | KDM4E 4164/4885LMNA 3768/4885SMN1; SMN2 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.