Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14447291 | 0.93 | KDM4E (0.37) | PDK2KDM4ELMNASMN1; SMN2PSMB5 | |
| SCHEMBL12146661 | 0.92 | TDP1 (0.43) | KDM4ELMNASMN1; SMN2PSMB5ALDH1A1 | |
| SCHEMBL12690749 | 0.91 | TDP1 (0.39) | PDK2KDM4ELMNASMN1; SMN2PSMB5 | |
| SCHEMBL12146660 | 0.91 | TDP1 (0.42) | KDM4ELMNASMN1; SMN2PSMB5ALDH1A1 | |
| SCHEMBL14270744 | 0.90 | PDK2 (0.42) | PDK2KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15081595 | 0.90 | PDK2 (0.42) | PDK2KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14036996 | 0.90 | PDK2 (0.42) | PDK2KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20707495 | 0.90 | PDK2 (0.42) | PDK2KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL16158299 | 0.90 | PDK2 (0.42) | PDK2KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL18926277 | 0.90 | PDK2 (0.42) | PDK2KDM4ELMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9324951-B2 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2016-04-26 | — | — | US | disclosed |
| US-9324951-B2 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2016-04-26 | — | — | US | disclosed |
| US-20150112065-A1 | Pyrazine Derivative, and Light Emitting Element, Display Device, Electronic Device Using the Pyrazine Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2015-04-23 | — | — | US | disclosed |
| US-20150112065-A1 | Pyrazine Derivative, and Light Emitting Element, Display Device, Electronic Device Using the Pyrazine Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2015-04-23 | — | — | US | disclosed |
| US-8920941-B2 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-12-30 | — | — | US | disclosed |
| US-8920941-B2 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-12-30 | — | — | US | disclosed |
| US-20070161793-A1 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161793-A1 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161793-A1 | Pyrazine derivative, and light emitting element, display device, electronic device using the pyrazine derivative | GRIA1, GRIN1, GRIA2 | PDK2 107/4885KDM4E 4164/4885LMNA 3768/4885 |
| US-20150112065-A1 | Pyrazine Derivative, and Light Emitting Element, Display Device, Electronic Device Using the Pyrazine Derivative | GRIA1, GRIN1, GRIA2 | PDK2 107/4885KDM4E 4164/4885LMNA 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.