Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444737 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TDP1L3MBTL1CES2ACHE | |
| SCHEMBL11356765 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1CES2ACHE | |
| 2-Nitroanisole SCHEMBL29434934 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| 1,2-Dimethoxybenzene SCHEMBL27460764 | 0.80 | ALDH1A1 (0.84) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| 2-Nitroanisole SCHEMBL20328416 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| 2-Nitroanisole SCHEMBL186551 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL1405477 | 0.80 | CA1 (0.60) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL1405475 | 0.80 | CA1 (0.60) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL29040523 | 0.80 | KMT2A (0.50) | ALDH1A1TDP1L3MBTL1CES2ACHE | |
| SCHEMBL4283506 | 0.80 | KMT2A (0.54) | ALDH1A1TDP1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406794-A1 | OPTICAL POWER LIMITING POLYMERIC MATRIX | Oxazogen, Inc. (US) | 2012-01-18 | — | — | EP | disclosed |
| WO-2011037619-A1 | POLYMERIC DYE FOR OPTICAL POWER LIMITING | OXAZOGEN, INC. (US) | 2011-03-31 | — | — | WO | disclosed |