Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282581 | 0.91 | TSHR (0.54) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| Ethylene SCHEMBL6410194 | 0.89 | TSHR (0.51) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14448350 | 0.87 | MAPK1 (0.53) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3247280 | 0.87 | CYP3A4 (0.49) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14713356 | 0.86 | TSHR (0.48) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3854017 | 0.83 | TUBB4A (0.48) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8323174 | 0.83 | SMPD1 (0.48) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8337903 | 0.83 | SMPD1 (0.48) | TSHRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3854627 | 0.80 | NPC1 (0.55) | ACHEMAPTBCHESMN1; SMN2 | |
| SCHEMBL3234539 | 0.80 | NPC1 (0.55) | ACHEMAPTBCHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161628-A1 | Phosphodiesterase inhibitors | GREENPHARMA (FR) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161628-A1 | Phosphodiesterase inhibitors | PDE5A, PDE3A, PDE3B | TSHR 2368/4885CYP2C19 138/4885CYP1A2 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.