⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20645879 | 1.00 | — | — | |
| SCHEMBL22328066 | 0.87 | — | — | |
| SCHEMBL24269599 | 0.71 | — | — | |
| SCHEMBL2023904 | 0.70 | PDE8B (0.33) | — | |
| SCHEMBL2023900 | 0.70 | PDE8B (0.33) | — | |
| SCHEMBL2023903 | 0.70 | PDE8B (0.33) | — | |
| SCHEMBL2025052 | 0.70 | PDE8B (0.33) | — | |
| SCHEMBL2025053 | 0.70 | PDE8B (0.33) | — | |
| SCHEMBL2023906 | 0.70 | PDE8B (0.33) | — | |
| SCHEMBL20640999 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |