Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 5/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730466 | 0.99 | KDM4E (0.36) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14468952 | 0.90 | THRA (0.30) | THRATHRB | |
| Bromide SCHEMBL1732469 | 0.88 | KDM4E (0.37) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| Bromide SCHEMBL1731328 | 0.88 | KDM4E (0.37) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| Bromide SCHEMBL1732608 | 0.88 | F2R (0.39) | KDM4EMAPTRAB9ANPC1F2R | |
| SCHEMBL14449148 | 0.88 | F2R (0.40) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| Bromide SCHEMBL1731761 | 0.88 | F2R (0.36) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| Bromide SCHEMBL1731032 | 0.87 | F2R (0.40) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| Bromide SCHEMBL1730945 | 0.86 | F2R (0.37) | KDM4EMAPTRAB9ANPC1F2R | |
| Bromide SCHEMBL1729841 | 0.86 | KDM4E (0.35) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |