SCHEMBL14449152

SCHEMBL14449152

CCOc1cc2c(c(F)c1OCC)C(=N)N(CC(=O)c1cc(N3CCCC3)c(OC)c(C(C)(C)C)c1)C2

nearest known ligand 0.87

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2R P25116 17/20 0.87
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13144389 0.99 F2R (0.86) F2RGAASMN1; SMN2MAPT
Bromide SCHEMBL1730235 0.99 F2R (0.87) F2RGAASMN1; SMN2MAPT
SCHEMBL13950221 0.94 F2R (0.85) F2RMAPT
SCHEMBL13628887 0.93 F2R (0.88) F2RGAA
SCHEMBL1732138 0.93 F2R (0.98) F2R
Atopaxar SCHEMBL30175034 0.93 F2R (1.00) F2RGAASMN1; SMN2MAPT
Atopaxar SCHEMBL1730339 0.93 F2R (1.00) F2RGAASMN1; SMN2MAPT
SCHEMBL1732773 0.93 F2R (0.84) F2RMAPT
Hydrochloric Acid SCHEMBL1728751 0.93 F2R (1.00) F2R
Atopaxar SCHEMBL1729065 0.93 F2R (0.98) F2RGAASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7244730-B2 2-iminopyrrolidine derivatives EISAI CO., LTD (JP) 2007-07-17 US disclosed