Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017062 | 0.92 | PPARD (0.41) | PPARDPPARAPPARGESR1 | |
| SCHEMBL4655286 | 0.91 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL14449262 | 0.87 | PPARD (0.39) | PPARDPPARAPPARGESR1 | |
| SCHEMBL14016243 | 0.87 | PPARD (0.42) | PPARDPPARAPPARGESR1 | |
| SCHEMBL14449268 | 0.86 | PPARD (0.41) | PPARDPPARAPPARGESR1 | |
| SCHEMBL14449269 | 0.86 | PPARD (0.37) | PPARDPPARAPPARGESR1 | |
| SCHEMBL4654136 | 0.84 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL1034264 | 0.83 | ESR1 (0.43) | PPARDPPARAPPARGESR1 | |
| SCHEMBL14449274 | 0.82 | PPARD (0.46) | PPARDPPARAPPARGESR1 | |
| SCHEMBL14449265 | 0.82 | PPARD (0.44) | PPARDPPARAPPARGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155805-A1 | Benzofuran and bezothiophene derivatives useful for the treatment of cardiovascular disease | SMITHKLINE BEECHAM CORPORATION | 2007-07-05 | — | — | US | disclosed |
| US-20070155805-A1 | Benzofuran and bezothiophene derivatives useful for the treatment of cardiovascular disease | SMITHKLINE BEECHAM CORPORATION | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155805-A1 | Benzofuran and bezothiophene derivatives useful for the treatment of cardiovascular disease | ABAT, BPTF, TNNT2 | PPARD 47/4885PPARA 115/4885PPARG 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.