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Sugi Predict / Targets / TNNT2

TNNT2

Troponin T, cardiac muscle (TnTc) (Cardiac mu · P45379 · TNNT2 on Sugi Atlas →

12,089 patent compounds predicted against TNNT2, 9,027 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2058443 SCHEMBL2058443 0.54 3/20
SCHEMBL2058445 SCHEMBL2058445 0.54 3/20
SCHEMBL1959899 SCHEMBL1959899 0.51 3/20
SCHEMBL1959900 SCHEMBL1959900 0.51 3/20
Sennoside A Sennoside A (SCHEMBL440792) 1.00 2/20
Sennoside B Sennoside B (SCHEMBL441194) 1.00 2/20
SCHEMBL722959 SCHEMBL722959 0.57 2/20
SCHEMBL940116 SCHEMBL940116 0.56 2/20
SCHEMBL1706253 SCHEMBL1706253 0.56 2/20
SCHEMBL1599043 SCHEMBL1599043 0.56 2/20
SCHEMBL941002 SCHEMBL941002 0.53 2/20
Aloin Aloin (SCHEMBL181616) 0.52 2/20
SCHEMBL1710516 SCHEMBL1710516 0.51 2/20
SCHEMBL244406 SCHEMBL244406 0.51 2/20
SCHEMBL1894380 SCHEMBL1894380 0.51 2/20
SCHEMBL939398 SCHEMBL939398 0.50 2/20
SCHEMBL1348301 SCHEMBL1348301 0.48 2/20
SCHEMBL1348304 SCHEMBL1348304 0.48 2/20
SCHEMBL814860 SCHEMBL814860 0.46 2/20
SCHEMBL814861 SCHEMBL814861 0.46 2/20

Clinical trials — most relevant to TNNT2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Acute Chest Pain Treatment and Evaluation (ACTION) Study PHASE4COMPLETED
Study to Evaluate the Safety, Tolerability, and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Children PHASE3COMPLETED
Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings nanUNKNOWN
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease nanACTIVE_NOT_RECRUITING
Sleep Disordered Breathing in Acute Congestive Heart Failure nanCOMPLETED
SpinChip Hs-cTnI Determination of the 99th Percentile URL nanCOMPLETED
A Cardiac Registry to Evaluate and Manage the hsTnI Categorical CVD Risk in Subjects Undergoing Preventive Health Checks (PHC). nanSUSPENDED
Finding Acute Coronary Syndromes (ACS) With Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms nanUNKNOWN
Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care nanCOMPLETED
Hs-cTn - Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women nanACTIVE_NOT_RECRUITING
TROPOnin FRAGMentation in Myocardial Injury Study nanRECRUITING
Rheumatoid Arthritis Disease Activity and Sub Clinical Atherosclerosis nanCOMPLETED
Risk Markers in the Acute Coronary Syndromes nanCOMPLETED
ARgentinean Risk Assessment Registry in ACS; the ARRA-RACS Study nanCOMPLETED
Observational Study on Cardiac Biomarkers Testing in Patients with Muscular Dystrophy Cardiomyopathy nanCOMPLETED
SpinChip Hs-cTnI Sample Type Validation nanCOMPLETED
COronary Microcirculation and Troponin Elevation in Septic Shock nanCOMPLETED
Cardiac Injury With Convulsive Status Epilepticus nanUNKNOWN
Hypersensitive Troponin Performance to Identify Syncope at Risk of Serious Adverse Events in the Short Term nanUNKNOWN
Cardiotoxicity and Risk Factors in Patients With Colorectal Cancer Receiving Fluoropyrimidine nanUNKNOWN
Troponin T and Emergency High-risk Abdominal Surgery nanUNKNOWN
SpinChip Hs-cTnI Clinical Diagnostic Performance nanCOMPLETED
Study of High Sensitive Troponin-I Level in End-stage Renal Disease Patients Receiving Hemodialysis nanCOMPLETED
Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes nanCOMPLETED
SpinChip Hs-cTnI Multisite Precision nanCOMPLETED
The CASABLANCA Study: Catheter Sampled Blood Archive in Cardiovascular Diseases nanCOMPLETED
Cardiac Injury in Patients With Influenza nanUNKNOWN
A Comparison of p53-induced Genes Activation in Patients With and Without Acute Myocardial Infarction nanCOMPLETED
Cardiac Troponin Fragmentation After Heavy Physical Exercise The MaraCat2 Study nanUNKNOWN
Cardiac Magnetic Resonance Imaging Strategy for the Management of Patients With Acute Chest Pain and Detectable to Elevated Troponin nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TNNT2 binder may also engage these)

ProteinNameSimilarity
Q7TNB2 — 1.000 Q7TNB2 →
P50753 — 0.999 P50753 →
P50751 — 0.997 P50751 →
P09741 — 0.996 P09741 →
Q75NG9 — 0.996 Q75NG9 →
P50752 — 0.994 P50752 →
P02642 — 0.993 P02642 →
P12620 — 0.993 P12620 →
Q75ZZ6 — 0.992 Q75ZZ6 →
Q8MKI3 — 0.992 Q8MKI3 →
P45378 — 0.991 P45378 →
Q9QZ47 — 0.991 Q9QZ47 →
P13789 — 0.990 P13789 →
Q8MKH6 — 0.989 Q8MKH6 →
O88346 — 0.989 O88346 →
P06398 — 0.988 P06398 →
P02641 — 0.987 P02641 →
P13805 — 0.984 P13805 →
P19351 — 0.983 P19351 →
P09739 — 0.982 P09739 →
Q863B6 — 0.973 Q863B6 →
Q9XZ71 — 0.973 Q9XZ71 →
Q9CWV6 — 0.971 Q9CWV6 →
P23693 — 0.971 P23693 →
Q5BJP2 — 0.971 Q5BJP2 →
Q5PYI0 — 0.970 Q5PYI0 →
Q8MKD5 — 0.969 Q8MKD5 →
TNNI3 Troponin I, cardiac muscle (Cardiac troponin 0.968 landscape →
Q6NUB2 — 0.968 Q6NUB2 →
P04975 — 0.968 P04975 →