Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23284298 | 0.73 | ACHE (0.41) | ACHEBRD4CREBBPHTR2AHTR2C | |
| SCHEMBL19454304 | 0.67 | CYP1A2 (0.35) | ACHEHTR2AHTR2C | |
| SCHEMBL21657656 | 0.67 | CREBBP (0.50) | ACHEBRD4CREBBPAKR1B1MAOB | |
| SCHEMBL29924512 | 0.67 | ACHE (0.42) | ACHEHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL7916564 | 0.67 | CREBBP (0.50) | ACHEBRD4CREBBPAKR1B1MAOB | |
| SCHEMBL10391638 | 0.67 | ACHE (0.42) | ACHEHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL27416977 | 0.67 | ACHE (0.36) | ACHEHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL14449359 | 0.67 | KDM4E (0.33) | — | |
| SCHEMBL12433390 | 0.66 | ACHE (0.41) | ACHEBRD4CREBBPHTR2AHTR2C | |
| SCHEMBL10262979 | 0.66 | ACHE (0.41) | ACHEBRD4CREBBPHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |