Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449331 | 0.86 | AKR1B1 (0.40) | AKR1B1BRD4CREBBPPTGS2 | |
| SCHEMBL14449375 | 0.71 | BRD4 (0.32) | AKR1B1BRD4CREBBPPTGS2 | |
| SCHEMBL14449381 | 0.71 | CYP19A1 (0.40) | AKR1B1BRD4CREBBP | |
| SCHEMBL15253570 | 0.69 | MAOB (0.35) | AKR1B1BRD4CREBBPPTGS2MAOB | |
| SCHEMBL8282240 | 0.69 | CREBBP (0.40) | AKR1B1BRD4CREBBPPTGS2MAOB | |
| SCHEMBL19122771 | 0.66 | CREBBP (0.38) | AKR1B1BRD4CREBBPPTGS2MAOB | |
| SCHEMBL26476510 | 0.66 | CYP1A2 (0.33) | MAOB | |
| SCHEMBL17193805 | 0.64 | HTR2C (0.36) | BRD4CREBBPMAOB | |
| SCHEMBL13475983 | 0.64 | ACHE (0.40) | AKR1B1BRD4CREBBPMAOB | |
| SCHEMBL14449384 | 0.64 | ACHE (0.40) | AKR1B1BRD4CREBBPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |