SCHEMBL14449652

SCHEMBL14449652

CCc1ccc(-c2ccc3c(c2)CCC(c2cc(F)c(F)c(F)c2)O3)cc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
FFAR4 Q5NUL3 9/20 0.35
RORC P51449 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
CACNA1C Q13936 1/20 0.34
SCN5A Q14524 1/20 0.34
FFAR1 O14842 6/20 0.34
PTPN1 P18031 1/20 0.33
GPR119 Q8TDV5 1/20 0.33
SLC8A1 P32418 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14449663 0.85 CSF1R (0.31)
SCHEMBL4638432 0.79 ESR1 (0.40) ESR1ESR2CYP4F2CYP4A11FFAR1
SCHEMBL14144587 0.78 ESR1 (0.48) ESR1ESR2CACNA1CSCN5APTPN1
SCHEMBL5482894 0.76 GPR119 (0.32) GPR119
SCHEMBL14449654 0.74 ESR1 (0.40) ESR1ESR2FFAR4FFAR1
SCHEMBL4372389 0.74 ESR2 (0.76) ESR1ESR2CYP4F2CYP4A11FFAR1
SCHEMBL14449675 0.73 ESR1 (0.37) ESR1ESR2CYP4F2CYP4A11FFAR1
SCHEMBL4639355 0.73 CTSC (0.31)
SCHEMBL14144578 0.71 ESR1 (0.43) ESR1ESR2FFAR4FFAR1
SCHEMBL14449677 0.69 ESR1 (0.42) ESR1ESR2FFAR1SLC8A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247355-B2 Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition CHISSO CORPORATION (JP) 2007-07-24 US disclosed
US-7247355-B2 Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition CHISSO CORPORATION (JP) 2007-07-24 US disclosed