Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445083 | 0.84 | PIK3R1 (1.00) | PIK3R1PIK3CA | |
| SCHEMBL12819811 | 0.82 | PIK3R1 (0.70) | PIK3R1PIK3CA | |
| SCHEMBL16612929 | 0.80 | PIK3CA (0.66) | PIK3R1PIK3CA | |
| SCHEMBL632091 | 0.76 | PIK3CA (0.69) | PIK3R1PIK3CA | |
| SCHEMBL14725953 | 0.74 | PIK3CA (0.69) | PIK3R1PIK3CA | |
| SCHEMBL12820308 | 0.73 | PIK3CA (0.56) | PIK3R1PIK3CA | |
| SCHEMBL16881781 | 0.73 | PIK3CA (0.74) | PIK3R1PIK3CA | |
| SCHEMBL5554598 | 0.72 | PIK3CA (0.64) | PIK3R1PIK3CA | |
| SCHEMBL622969 | 0.71 | PIK3CA (0.55) | PIK3R1PIK3CA | |
| SCHEMBL893488 | 0.71 | PIK3CA (1.00) | PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480549-B1 | Fused imidazo[3,2-d]pyrazines as PI3 kinase inhibitors | FUNDACIÓN CT NAC DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (ES) | 2015-04-08 | — | — | EP | disclosed |
| EP-2480549-A1 | FUSED IMIDAZO [3, 2 - D]PYRAZINES AS PI3 KINASE INHIBITORS | Centro Nacional de Investigaciones Oncológicas (CNIO) (ES) | 2012-08-01 | — | — | EP | disclosed |
| WO-2011036461-A1 | FUSED IMIDAZO [3, 2 - D] PYRAZINES AS PI3 KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCΌLOGICAS (CNIO) (ES) | 2011-03-31 | — | — | WO | disclosed |