Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LHCGR | P22888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12273067 | 0.91 | SLC22A12 (0.37) | TP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL2414510 | 0.89 | PPARA (0.41) | TP53PPARAPOLB | |
| Hydrochloric Acid SCHEMBL2414184 | 0.89 | PPARA (0.41) | TP53PPARAPOLB | |
| SCHEMBL12273185 | 0.87 | SLC22A12 (0.43) | TP53MAPTLMNAPPARA | |
| Trifluoroacetic Acid SCHEMBL2412639 | 0.87 | LMNA (0.36) | TP53MAPTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2419340 | 0.86 | SLC22A12 (0.43) | TP53MAPTLMNAPPARA | |
| SCHEMBL12271943 | 0.86 | PIM1 (0.40) | TP53FYN | |
| SCHEMBL2415288 | 0.86 | CTSA (0.39) | TP53MAPTLMNAPPARATHRB | |
| Hydrochloric Acid SCHEMBL2414359 | 0.86 | PIM1 (0.39) | TP53FYN | |
| SCHEMBL12273188 | 0.85 | SLC22A12 (0.42) | TP53ABL1MAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |